GLP-1 / Metabolic
Semaglutide
GLP-1 receptor agonist — the active ingredient in Ozempic and Wegovy.
Educational only. Not medical advice. Dosages listed reflect what is commonly reported in research and user communities — consult a licensed physician before self-administering.
Typical dose
0.25 mg weekly, titrating up to 2.4 mg weekly over 16+ weeks
Route
Subcutaneous
Half-life
~7 days
Cycle
Indefinite under medical supervision
What it does
- Clinically proven weight loss (15%+ body weight in STEP trials)
- Improved glycemic control in type 2 diabetes
- Reduced appetite and food noise
- Cardiovascular risk reduction in high-risk populations
Honest limitations
- Prescription drug — obtaining outside a licensed prescriber is illegal in most countries
- Weight regain is common after discontinuation
- Muscle loss can occur without adequate protein + resistance training
Reconstitution example
Vial size
5 mg
BAC water
2.5 ml
Concentration
2.00 mg/ml
To dose 0.25 mg, draw 12.5 units on a U-100 insulin syringe.
Open the calculator with your own numbers →Injection
Route
Subcutaneous
Needle
29–31g insulin syringe (0.3–0.5 ml)
Timing
Same day each week, any time
Stacking
Best paired with high-protein diet and resistance training to preserve lean mass.
Side effects
- Nausea, especially during titration
- Constipation or diarrhea
- Fatigue
- Rare: pancreatitis, gallbladder issues
Contraindications
- Personal or family history of medullary thyroid carcinoma
- MEN2 syndrome
- History of pancreatitis
- Pregnancy
Semaglutide protocol PDF — $9
Printable Semaglutide protocol card: dosing tables, reconstitution math, cycle length, and reference literature. Instant PDF download.
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Where to buy
Vendors we've reviewed that publish third-party certificates of analysis.
Buy Semaglutide at Rebirth Labs →