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Educational content · Not medical advice · Consult a licensed physician
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GLP-1 / Metabolic

Retatrutide

Triple agonist (GLP-1 / GIP / glucagon) — Phase 3 obesity candidate showing >24% weight loss.

Educational only. Not medical advice. Dosages listed reflect what is commonly reported in research and user communities — consult a licensed physician before self-administering.
Typical dose
2 mg weekly, titrating up to 8–12 mg weekly
Route
Subcutaneous
Half-life
~6 days
Cycle
Under study

What it does

  • Highest weight loss of any peptide in trials to date
  • Improved insulin sensitivity
  • Reduced hepatic fat

Honest limitations

  • Not yet FDA approved — investigational drug
  • Long-term safety unknown
  • GI side effects common

Reconstitution example

Vial size
10 mg
BAC water
2 ml
Concentration
5.00 mg/ml
To dose 2 mg, draw 40 units on a U-100 insulin syringe.
Open the calculator with your own numbers →

Injection

Route
Subcutaneous
Needle
29–31g insulin syringe
Timing
Same day each week
Stacking
Do not stack with other GLP-1 agonists.
Full injection technique guide →

Side effects

  • Nausea, vomiting, diarrhea
  • Increased heart rate
  • Fatigue

Contraindications

  • MTC/MEN2 history
  • Pancreatitis history
  • Pregnancy

Retatrutide protocol PDF — $9

Printable Retatrutide protocol card: dosing tables, reconstitution math, cycle length, and reference literature. Instant PDF download.

Where to buy

Vendors we've reviewed that publish third-party certificates of analysis.

Buy Retatrutide at Rebirth Labs

Sources